​OUR TECHNOLOGY

Opharmic specializes in the development of ultrasound-mediated technologies and devices for non-invasive ocular drug delivery for a variety of eye diseases and conditions.

Mechanism - Acoustic Micro-streaming

During ultrasound radiation, cavities would respond to the fundamental driving frequency in form of periodic oscillations. Micro-stream flows are generated as a result of the periodic oscillations of the cavities.

​With Opharmic's proprietary ultrasound technology, delivery of drugs into the eye can be optimized by precisely controlling the micro-stream flow. 

A Pommella et al, Nature, 2015

On the cellular level, it is known that cellular membranes are intrinsically capable of receiving and responding to mechanical stimuli.

​​Our ultrasound technology can be precisely engineered to stimulate the cellular transport activities and to modulate the barrier properties of the eye tissue or enhanced drug uptake.

LJ Rizzolo et al, Prog. Retin. Eye Res., 2011

Our Solution

Developed by Opharmic Technology aiming to replace needle injections, the needle-less Sonikure device safely and efficiently deliver drugs into the eye using the low energy ultrasonic technology. 

​Compatible to market-available injectables, it is a platform technology that can treat a wide range of diseases.